Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264 [Microbiology]

Bacteria produce a diverse array of secondary metabolites that have been invaluable in the clinic and in research. These metabolites are synthesized by dedicated biosynthetic gene clusters (BGCs), which assemble architecturally complex molecules from simple building blocks. The majority of BGCs in a given bacterium are not expressed under normal...

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