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Δευτέρα 22 Μαΐου 2017

Nickel-Catalyzed Hydrocarboxylation of Ynamides with CO2 and H2O: Observation of Unexpected Regioselectivity

Chem. Commun., 2017, Accepted Manuscript
DOI: 10.1039/C7CC03127K, Communication
Ryohei Doi, Iman Abdullah, Takahisa Taniguchi, Nozomi Saito, Yoshihiro Sato
We describe the nickel-catalyzed hydrocarboxylation of ynamides with CO2 and H2O to afford a variety of [small alpha]-amino-[small alpha],[small beta]-unsaturated esters with high regioselectivities. Selective [small alpha]-carboxylation of ynamide with this catalytic protocol is...
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