Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis [Immunology and Inflammation]

The presence of the endogenous Leishmania RNA virus 1 (LRV1) replicating stably within some parasite species has been associated with the development of more severe forms of leishmaniasis and relapses after drug treatment in humans. Here, we show that the disease-exacerbatory role of LRV1 relies on type I IFN (type...

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