A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome [Biophysics and Computational Biology]

In the scanning model of translation initiation, the decoding site and latch of the 40S subunit must open to allow the recruitment and migration of messenger RNA (mRNA); however, the precise molecular details for how initiation factors regulate mRNA accommodation into the decoding site have not yet been elucidated. Eukaryotic...

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