We read with great interest the article by Mok et al1 about the role of lactated Ringer's (LR) solution with rectal indomethacin (IND) for the prevention of post-ERCP pancreatitis (PEP) and readmission rates. The authors compared 4 treatment arms: LR + IND, LR + placebo, normal saline solution (NS) + placebo, and NS + IND. They reported that the choice of fluid is important because the best protocol for prevention of PEP was reported to be LR + IND, inasmuch as the rate of PEP in this group was lowest compared with all of the other groups.
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