Structure of the C1 complex of complement [Biological Sciences]

In PNAS, Mortensen et al. (1) propose a model of the C1 complex of complement derived from small-angle X-ray scattering (SAXS) and electron microscopy (EM) analyses that contradicts previously published models and suggests an intermolecular activation process. This proposal is largely derived from a conjectural structure of C1r2C1s2, the catalytic...

http://ift.tt/2vfpIp6