Knowledge of food protein–induced enterocolitis syndrome among general pediatricians

Food protein–induced enterocolitis syndrome (FPIES) is a potentially severe, non–IgE-mediated food hypersensitivity. Typically, FPIES presents in infancy, either acutely with profuse emesis, dehydration, and lethargy 1 to 4 hours after intermittent ingestions; or insidiously with frequent, watery diarrhea, intermittent emesis, and failure to thrive with chronic ingestions.1 Common eliciting foods include cow's milk and soy proteins; solids (rice, oat, fish, poultry, fish, and shellfish) are also culprits.

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