Potential impact of biologics and emerging therapies for psoriasis and atopic dermatitis on future fertility: Reassurance to patients but more data are needed

To the Editor: For young patients suffering from atopic dermatitis, plaque psoriasis, and alopecia areata, new targeted therapies offer significant promise. The majority of these conditions present in individuals of reproductive age.1 Thus, there is a need to understand how new systemic drugs affect future fertility. In oncology, adverse effect on fertility is an important consideration for treatment selection. In dermatology, established systemic medications such as methotrexate and cyclosporine have known fertility risks, including impaired spermatogenesis and sperm motility in humans.

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