A woman was diagnosed with common variable immunodeficiency (CVID) at the age of 42 years. She began having infections when she was 24 years of age. Her history included chronic sinusitis and 3 bacterial pneumonias at different times in both lungs. Her infections necessitated antibiotic therapy almost every other month. A specialist in allergy and immunology finally made the diagnosis of immune deficiency and, specifically, CVID on testing. Her immunoglobulin levels were extremely low: serum IgG, 250 mg/dL; IgA, less than 7 mg/dL; and IgM, 40 mg/dL.
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