A case of midazolam anaphylaxis during a pediatric patient's first anesthetic

Perioperative anaphylaxis remains a relatively rare (with an estimated incidence 1:3,5000 to 1:20,000) but important cause of morbidity and mortality [1]. Common causes include neuromuscular blockers, antibiotics, and latex [1,2]. Diagnosis of perioperative anaphylaxis may be delayed, as general anesthesia may mask the characteristic symptoms of hypotension, rash, and airway swelling. Herein we present a case of midazolam anaphylaxis in a child's first anesthetic.

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