Vancomycin is one of the most widely used antibiotics and, because of its prevalent use, several common side effects have been well described, such as "red man" syndrome, agranulocytosis, and ototoxicity. In addition, it has been associated with hypersensitivity reactions including immunoglobulin E–mediated anaphylaxis, linear immunoglobulin A (IgA) bullous dermatosis (LABD), drug reaction with eosinophilia and systemic symptoms syndrome, acute interstitial nephritis, and Stevens-Johnson syndrome and toxic epidermal necrolysis.
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