Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth [Immunology and Inflammation]

IL-22 has been identified as a cancer-promoting cytokine that is secreted by infiltrating immune cells in several cancer models. We hypothesized that IL-22 regulation would occur at the interface between cancer cells and immune cells. Breast and lung cancer cells of murine and human origin induced IL-22 production from memory...

http://ift.tt/2jVvvv1