Τετάρτη 13 Δεκεμβρίου 2017

Direct detection of lysine side chain NH3+ in protein-heparin complexes using NMR spectroscopy

Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C7AN01406F, Communication
Krishna Mohan Sepuru, Junji Iwahara, krishna rajarathnam
Two NMR observables, N[small zeta]H3+ peak in the HISQC spectrum and N[small zeta] chemical shift difference between the free and heparin-bound forms, can identify binding-interface lysines in protein-heparin complexes. Unlike backbone chemical...
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