Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis [Plant Biology]

Genome-wide characterization by next-generation sequencing has greatly improved our understanding of the landscape of epigenetic modifications. Since 2008, whole-genome bisulfite sequencing (WGBS) has become the gold standard for DNA methylation analysis, and a tremendous amount of WGBS data has been generated by the research community. However, the systematic comparison of...

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