Author's response to ‘fractional exhaled nitric oxide: signaling lung function changes in obstructive lung diseases.’

We would like to express our appreciation to the authors of the correspondence in response to our article. Fractional exhaled nitric oxide (FeNO) is known as a noninvasive biomarker reflecting allergic airway inflammation in asthma. Some reports have suggested relationships between FeNO and both bronchial hyperresponsiveness and airway obstruction. In our study, we concluded that elevated mean FeNO levels may indicate annual declines of forced expiratory volume in one second (FEV1) in asthmatic subjects.

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