Exposure to tobacco smoke (ETS) has been associated with increased risk for severity of asthma in children [1,2]. The question to be addressed is whether children with asthma with high environmental tobacco exposure would respond as well to inhaled corticosteroids as those with lower ETS exposure. Urine cotinine is a sensitive and specific biomarker for measuring the exposure to tobacco smoke. The aim of the study was to assess whether the high exposure to tobacco smoke measured by urine cotinine level can influence the daily dose of inhaled corticosteroids needed to achieve asthma control in exposed children.
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