COBLL1 modulates cell morphology and facilitates androgen receptor genomic binding in advanced prostate cancer [Medical Sciences]

Androgen receptor (AR) signaling is essential for prostate cancer progression and acquiring resistance to hormone therapy. However, the molecular pathogenesis through AR activation has not been fully understood. We performed integrative transcriptomic analysis to compare the AR program in a castration-resistant prostate cancer (CRPC) model with that in their parental...

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