The glycolipid GM1 reshapes asymmetric biomembranes and giant vesicles by curvature generation [Chemistry]

The ganglioside GM1 is present in neuronal membranes at elevated concentrations with an asymmetric spatial distribution. It is known to generate curvature and can be expected to strongly influence the neuron morphology. To elucidate these effects, we prepared giant vesicles with GM1 predominantly present in one leaflet of the membrane,...

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