Transient pausing by RNA polymerase II [Cell Biology]

RNA polymerase II (Pol II) elongation control is utilized during transcription of most metazoan genes (1). Polymerases that successfully initiate must first break contacts with initiation factors and then interact with elongation factors including the DRB sensitivity-inducing factor (DSIF) and the negative elongation factor (NELF). This leads to a reduction...

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