Activated integrins identify functional antigen-specific CD8+ T cells within minutes after antigen stimulation [Immunology and Inflammation]

Immediate β2-integrin activation upon T cell receptor stimulation is critical for effective interaction between T cells and their targets and may therefore be used for the rapid identification and isolation of functional T cells. We present a simple and sensitive flow cytometry-based assay to assess antigen-specific T cells using fluorescent...

https://ift.tt/2HHomZn