Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy [Cell Biology]

During HIV-1 assembly, the retroviral structural protein Gag forms an immature capsid, containing thousands of Gag molecules, at the plasma membrane (PM). Interactions between Gag nucleocapsid (NC) and viral RNA (vRNA) are thought to drive assembly, but the exact roles of these interactions have remained poorly understood. Since previous studies...

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