Synergistic Cytokine Effects as Apremilast Response Predictors in Patients With Psoriasis

Publication date: Available online 21 June 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Sandra Garcet, Kristine Nograles, Joel Correa da Rosa, Peter H. Schafer, James G. Krueger
•Based on nonlinear multivariate algorithms, IL-17F is the most important predictor of PASI improvement with apremilast, and nonlinear synergistic cytokine effects are more predictive of PASI response to apremilast than linear univariate models.



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