Transcriptional signature of the decidua in preeclampsia [Biological Sciences]

An emerging concept is that the genesis of preeclampsia is rooted in dysregulated decidualization (1). In PNAS, Garrido-Gomez et al. (2) demonstrate a distinct transcriptional signature in the endometrial stromal cells (ESCs) of preeclampsia patients compared with control cells during in vitro decidualization (before pregnancy) and in vivo decidualization (after...

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