Two Ck1{delta} transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock [Cell Biology]

The N6-methylation of internal adenosines (m6A) in mRNA has been quantified and localized throughout the transcriptome. However, the physiological significance of m6A in most highly methylated mRNAs is unknown. It was demonstrated previously that the circadian clock, based on transcription-translation negative feedback loops, is sensitive to the general inhibition of...

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