Perinatal maternal negative life events as risk factors of atopic dermatitis in female offspring

Prenatal maternal stress has been suggested as a factor that promotes the development of allergic diseases in the offspring.1 Maternal stress includes recognition of stressors (perceived stress) such as anxiety and depression and environmental stressors such as negative life events (NLEs): bereavement, loss of her or husband's job, separation, or divorce.1 Recently, we reported that prenatal maternal stress influenced the development of atopic dermatitis (AD) in offspring from two independent birth cohort study.

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