Systems genetic analysis of inversion polymorphisms in the malaria mosquito Anopheles gambiae [Applied Biological Sciences]

Inversion polymorphisms in the African malaria vector Anopheles gambiae segregate along climatic gradients of aridity. Despite indirect evidence of their adaptive significance, little is known of the phenotypic targets of selection or the underlying genetic mechanisms. Here we adopt a systems genetics approach to explore the interaction of two inversions...

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