Mucosal melanoma of the cranio-facial region: Surgical challenges and therapeutic options

The treatment of cutaneous melanoma (CM) and many other tumors has been revolutionized by new therapeutic options that are constantly improving the overall survival. However, the mucosal melanoma remains (MM) a rare tumor disease with a poor clinical outcome. MM is a neuroectodermal tumor arising from melanocytes. Precursors of melanocytes arise from the neural crest, from where they migrate to their final destination through embryonic mesenchyme, along specific pathways [1].

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