Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway [Biological Sciences]

We appreciate Bailey et al.'s (1) interest in our publication (2), in which we define a role for polymerase-δ interacting protein 2 (Poldip2) in controlling a salvage pathway of lipoylation. Our study builds on a substantial body of evidence, indicating that the mammalian mitochondrial lipoyltransferase LIPT1 lipoylates using lipoyl-AMP. While...

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