Penicillin allergy is the most frequently reported drug hypersensitivity reaction with a prevalence rate of around 10% in the US 1,2; however, true reactions exist in only around 3% of patients reporting a penicillin allergy 2. Penicillin allergy stigma results in higher health care costs and increased prevalence of multidrug resistant (MDR) organisms. In the pre-lung transplant population there are no data on penicillin skin testing in the setting of severely compromised lung function.
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