Phospholipid retention in the absence of asymmetry strengthens the outer membrane permeability barrier to last-resort antibiotics [Microbiology]

The outer membrane of Gram-negative bacteria is a critical barrier that prevents entry of noxious compounds. Integral to this functionality is the presence of lipopolysaccharide (LPS) or lipooligosaccharide (LOS), a molecule that is located exclusively in the outer leaflet of the outer membrane. Its lipid anchor, lipid A, is a...

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