A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice [Neuroscience]

Sleep is an evolutionally conserved behavior from vertebrates to invertebrates. The molecular mechanisms that determine daily sleep amounts and the neuronal substrates for homeostatic sleep need remain unknown. Through a large-scale forward genetic screen of sleep behaviors in mice, we previously demonstrated that the Sleepy mutant allele of the Sik3...

https://ift.tt/2yuSC6W