Histopathology of primary lesion of erosive pustular dermatosis of the scalp has not been characterized. Biopsy of intact follicular pustules shows spongiotic vesiculo-pustules affecting the follicular infundibula. Erosive pustular dermatosis of the scalp is a neutrophilic superficial folliculitis, with some clinicopathologic similarities with other pathergic neutrophilic dermatoses, such as pyoderma gangrenosum.
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