Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection [Developmental Biology]

Cellular mosaicism due to monoallelic autosomal expression (MAE), with cell selection during development, is becoming increasingly recognized as prevalent in mammals, leading to interest in understanding its extent and mechanism(s). We report here use of clonal cell lines derived from the CNS of adult female F1 hybrid (C57BL/6 X JF1)...

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