Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches [Medical Sciences]

The bone is essential for locomotion, calcium storage, and harboring the hematopoietic stem cells (HSCs) that supply the body with mature blood cells throughout life. HSCs reside at the interface of the bone and bone marrow (BM), where active bone remodeling takes place. Although the cellular components of the BM...

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