TOXIC EPIDERMAL NECROLYSIS COMPLICATED BY CHRONIC INFLAMMATORY KERATITIS/CONJUNCTIVITIS AND INFLAMMATORY PERIPHERAL NEURITIS

We present a patient who developed chronic keratitis and conjunctivitis, inflammatory neuropathy of the hands, and onychomadesis as complications of her toxic epidermal necrolysis (TEN). Neuropathy was treated with glucocorticoids, methotrexate, and high dose IVIG; however the keratitis and conjunctivitis were resistant and required adalimumab. To the best of our knowledge, there are no other reports of inflammatory neuropathy as a sequelae of Stevens Johnson Syndrome (SJS)/TEN, nor management of chronic ocular inflammation with adalimumab.

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