African American Ancestry Contribution to Asthma and Atopic Dermatitis

Despite advances in therapeutics and a better understanding of environmental risk factors, racial disparities in both asthma and atopic dermatitis (AD) are profound, and cannot be explained by non-genetic factors alone1,2. Disparities are compounded by a disproportionate under-representation of minority populations in genetic and pharmacogenetic studies of asthma and AD. As a result, genetic risk factors for these clinical conditions are much less well understood in African ancestry populations compared to European populations.

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