Publication date: Available online 24 June 2019Source: ImmunityAuthor(s): Danielle A. Chisolm, Wayne Cheng, Shelby A. Colburn, Aaron Silva-Sanchez, Selene Meza-Perez, Troy D. Randall, Amy S. WeinmannSummaryGenetic variation influences how the genome is interpreted in individuals and in mouse strains used to model immune responses. We developed approaches to utilize next-generation sequencing datasets to identify sequence variation in genes and enhancer elements in congenic and backcross mouse models....
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