Early endosome as a pathogenic target for antiphosphatidylethanolamine antibodies [Medical Sciences]

Phosphatidylethanolamine (PE) is a major phospholipid species with important roles in membrane trafficking and reorganization. Accumulating clinical data indicate that the presence of circulating antibodies against PE is positively correlated with the symptoms of antiphospholipid syndromes (APS), including thrombosis and repeated pregnancy loss. However, PE is generally sequestered inside a...

http://ift.tt/2C6uGLh