The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression [Biochemistry]

The regulation of transcription allows cells to adjust the rate of RNA polymerases (RNAPs) initiated in a promoter-specific manner. Classically, transcription factors are directed to a subset of promoters via the recognition of DNA sequence motifs. However, a unique class of regulators is recruited directly through interactions with RNAP. Surprisingly,...

https://ift.tt/2C3JUzI