High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture [Biophysics and Computational Biology]

Rac1 activation is at the core of signaling pathways regulating polarized cell migration. So far, it has not been possible to directly explore the structural changes triggered by Rac1 activation at the molecular level. Here, through a multiscale imaging workflow that combines biosensor imaging of Rac1 dynamics with electron cryotomography,...

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