Publication date: May–June 2017
Source:Acta Otorrinolaringológica Española, Volume 68, Issue 3
Author(s): Gianluigi Grilli, Vanessa Suarez, María Gabriela Muñoz, María Costales, José Luis Llorente
Introducción y objetivosEl objetivo de este estudio es presentar nuestra experiencia en el diagnóstico y tratamiento de los tumores parafaríngeos.Pacientes y métodoRealizamos un estudio retrospectivo de 90 pacientes, diagnosticados y tratados quirúrgicamente de una tumoración parafaríngea entre 1984 y 2015. Fueron excluidos los pacientes cuyos tumores no eran primarios, sino que invadían esta región por contigüidad, los tumores originados en el lóbulo profundo de la parótida y las metástasis de otros tumores de cabeza y cuello.ResultadosEl 74% de las neoplasias del espacio parafaríngeo fueron de naturaleza benigna y el 26% maligna. Los adenomas pleomorfos fueron los tumores más frecuentes (27%), seguido por los paragangliomas (25%), un grupo de tumores de origen misceláneo de naturaleza maligna (16%), los tumores de origen neurogénico (12%), un grupo de tumores de origen misceláneo de naturaleza benigna (10%) y los tumores malignos de glándulas salivales (10%). El tratamiento fue quirúrgico en todos los casos. Se realizó un abordaje transcervical en 56 pacientes, un abordaje cervical-transparotídeo en 15 pacientes, un abordaje infratemporal tipo A en 13 pacientes, un abordaje transmandibular en 4 pacientes y en 2 casos un abordaje transoral. Las complicaciones más frecuentes fueron las derivadas de lesiones de estructuras nerviosas.ConclusionesLa mayoría de los tumores localizados en el espacio parafaríngeo son subsidiarios de ser tratados de forma quirúrgica con una baja tasa de complicaciones y recurrencias. El abordaje transcervical es el más utilizado.Introduction and objectivesThe aim of this study is to present our experience with the diagnostic and therapeutic approaches for parapharyngeal space tumours.Patients and methodThis study is a retrospective review of 90 patients diagnosed with tumours of the parapharyngeal space and treated surgically between 1984 and 2015. Patients whose tumours were not primary but invaded the parapharyngeal space expanding from another region, tumours originating in the deep lobe of the parotid gland and head and neck metastasis were excluded from this study.Results74% percent of the parapharyngeal space neoplasms were benign and 26% were malignant. Pleomorphic adenoma was the most common neoplasm (27%), followed by paragangliomas (25%), miscellaneous malignant tumours (16%), neurogenic tumours (12%), miscellaneous benign tumours (10%), and malignant salivary gland tumours (10%). The transcervical approach was used in 56 cases, cervical-transparotid approach in 15 cases, type A infratemporal fossa approach in 13 cases, transmandibular approach in 4 cases and transoral approach in 2 cases. The most common complications were those deriving from nervous injuries.ConclusionsMost parapharyngeal space tumours can be removed surgically with a low rate of complications and recurrence. The transcervical approach is the most frequently used.
http://ift.tt/2oYvesI
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- Tumores primarios del espacio parafaríngeo
- Gluteus medius muscle metastasis of squamous cell ...
- Temporal patterns of patient-reported trismus and ...
- Patient injuries in operative rhinology during a t...
- An Optimal Current Controller Design for a Grid Co...
- The effectiveness of earmuffs on the physiologic a...
- Immune responses and reconstitution in HIV-1 infec...
- From urban ecology to ecological urbanism: an ambi...
- The emerging role of innate immunity in protection...
- Effective immunity during late life; a possible ro...
- Molecular quantitation of thymic output in mice an...
- Immune reconstitution in HIV-1-infected patients.
- Enhanced T cell maturation, differentiation and fu...
- Stimulation of cell surface CCR5 and CD40 molecule...
- Thymic activity in late-stage HIV-1 infected indiv...
- Thymic output during initial HAART and during HAAR...
- Transient nature of long-term nonprogression and b...
- Correction: The effect of allogeneic in vitro stim...
- Attention and visual texture segregation
- Neuronal Osmotransduction: Push-Activating TRPV1 w...
- The Extracellular Matrix Protein Artichoke Is Requ...
- TRP Channels in Insect Stretch Receptors as Insect...
- Modified mosquito landing boxes dispensing transfl...
- Auditory Efferent System Modulates Mosquito Hearing
- Three approaches to detecting discrete integrability
- Age-associated changes in thymopoiesis
- Fwd: Stroke and Nervous Diseases, Year 2016, Issue...
- Fwd: Cancer Research and Clinic, Year 2017, Issue ...
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Κυριακή 30 Απριλίου 2017
Tumores primarios del espacio parafaríngeo
Gluteus medius muscle metastasis of squamous cell carcinoma of larynx: a rare case
Publication date: Available online 29 April 2017
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Alperen Vural, Deniz Avcı, Sedat Çağlı, İmdat Yüce, Turan Arlı
http://ift.tt/2oMRY2D
Temporal patterns of patient-reported trismus and associated mouth-opening distances in radiotherapy for head and neck cancer: A prospective cohort study
Abstract
Objectives
To identify temporal patterns of patient-reported trismus during the first year post-radiotherapy, and to study their associations with maximal interincisal opening distances (MIOs).
Design
Single institution case series.
Setting
University hospital ENT clinic.
Participants
One hundred ninety six subjects who received radiotherapy (RT) for head and neck cancer (HNC) with or without chemotherapy in 2007-2012 to total dose of 64.6/68 Gy in 38/34 fractions, respectively. All subjects were prospectively assessed for mouth-opening ability (Gothenburg Trismus Questionnaire (GTQ), and MIO) pre-RT and at 3, 6, and 12 months after RT.
Main outcome measures
Correlations between temporally robust GTQ-symptoms and MIO as given by Pearson's correlation coefficients (Pr); temporally robust GTQ-symptom domains as given by factor analysis; rates of trismus with respect to baseline by risk ratios (RRs).
Results
Four temporally robust domains were identified: Eating (3-7 symptoms), Jaw (3-7), Pain (2-5), and Quality of Life (QoL, 2-5), and included 2-3 persistent symptoms across all post- RT assessments. The median RR for a moderate/severe (>2/>3) cut-off was the highest for Jaw (3.7/3.6) and QoL (3.2/2.9). The median Pr between temporally robust symptoms and MIO post-radiotherapy was 0.25-0.35/0.34-0.43/0.24-0.31/0.34-0.50 for Eating/Jaw/Pain/QoL, respectively.
Conclusions
Mouth-opening distances in HNC patients post-RT can be understood in terms of associated patient-reported outcomes on trismus-related difficulties. Our data suggest that a reduction in MIO can be expected as patients communicate their mouth-opening status to interfere with private/social life, a clinical warning signal for emerging or worsening trismus as patients are being followed after RT.
This article is protected by copyright. All rights reserved.
http://ift.tt/2pM424A
Patient injuries in operative rhinology during a ten-year period: Review of National Patient Insurance Charts
Abstract
Objectives
To assess factors contributing to patient injuries in operative rhinology.
Design
Data of the accepted patient injury claims involving operative rhinology, between the years 2001 and 2011, were obtained from the Finnish Patient Insurance Centre registry. Two senior otolaryngologists analysed and evaluated the injury mechanisms.
Main outcome measures
Analysis and classification of factors contributing to patient injuries.
Results
During the ten-year study period, there were 67 patient injuries in operative rhinology, comprising 36% of all patient injuries in otorhinolaryngologic surgery. The majority (78%) of patients were treated in university or central hospitals and almost all (90%) by fully trained otolaryngology specialists. The factors contributing to the injuries were errors in surgical technique, like lesions to the orbit, skull base and meninges, and adjacent nerves, as well as mistakes with removable packings left in situ. Nearly half of the patients had undergone endoscopic sinus surgery. One patient died because of bleeding from the intracranial artery. Fourteen patients (21%) needed a re-operation due to the injury.
Conclusions
Patient injuries in rhinology were caused by typical complications of common operations performed by otorhinolaryngology specialists. The increased volume of endoscopic sinus surgery was evident also in patient injuries.
This article is protected by copyright. All rights reserved.
http://ift.tt/2pv2aKo
An Optimal Current Controller Design for a Grid Connected Inverter to Improve Power Quality and Test Commercial PV Inverters
Grid connected inverters play a crucial role in generating energy to be fed to the grid. A filter is commonly used to suppress the switching frequency harmonics produced by the inverter, this being passive, and either an L- or LCL-filter. The latter is smaller in size compared to the L-filter. But choosing the optimal values of the LCL-filter is challenging due to resonance, which can affect stability. This paper presents a simple inverter controller design with an L-filter. The control topology is simple and applied easily using traditional control theory. Fast Fourier Transform analysis is used to compare different grid connected inverter control topologies. The modelled grid connected inverter with the proposed controller complies with the IEEE-1547 standard, and total harmonic distortion of the output current of the modelled inverter has been just 0.25% with an improved output waveform. Experimental work on a commercial PV inverter is then presented, including the effect of strong and weak grid connection. Inverter effects on the resistive load connected at the point of common coupling are presented. Results show that the voltage and current of resistive load, when the grid is interrupted, are increased, which may cause failure or damage for connecting appliances.
http://ift.tt/2ql38J6
The effectiveness of earmuffs on the physiologic and behavioral stability in preterm infants
Publication date: July 2017
Source:International Journal of Pediatric Otorhinolaryngology, Volume 98
Author(s): Nasrin Khalesi, Nastaran Khosravi, Azadeh Ranjbar, Zahra Godarzi, Alireza Karimi
BackgroundThe use of earmuffs can protect preterm infants against negative effects of high noise levels in the neonatal intensive care unit. This study was aimed at assessing the effectiveness of the earmuffs on the physiologic and behavioral responses in preterm infants.MethodsA crossed over controlled trial was conducted at Aliasghar Hospital (Tehran, Iran) in 2014. Thirty-six preterm infants cared in closed incubators, 18 cases wore a pair of silicon earmuffs in the first day and the others were worn it at the second day. During 2 consecutive days, all subjects were observed as their own controls (without earmuffs). Physiologic (body temperature, heart rate, respiratory rate, systolic, diastolic pressures, arterial Oxygen Saturation) and behavioral responses (according to the Anderson behavioral state scoring system) were assessed every 2 h for 8 h long during daytime for two consecutive days.ResultsThe application of earmuffs could decrease the rate of the heart and respiratory while could increase the amount of oxygen saturation (p < 0.05). The results also showed that the preterm infants with earmuffs had lower ABSS score and a better light sleep compared to those without earmuffs (2.38 ± 0.47 versus 4.8 ± 0.97, p < 0.05).ConclusionThe results indicated that using the earmuffs reduces the level of noise in NICUs following by improving the preterm neonates' physiological stability and behavioral states of ABSS.
http://ift.tt/2oLumM6
Immune responses and reconstitution in HIV-1 infected individuals: impact of anti-retroviral therapy, cytokines and therapeutic vaccination.
Pido, J; Imami, N; Hardy, G; Gazzard, B; Aspinall, R; Gotch, F; Immune responses and reconstitution in HIV-1 infected individuals: impact of anti-retroviral therapy, cytokines and therapeutic vaccination. Immunology Letters
http://ift.tt/2qrFQjY
From urban ecology to ecological urbanism: an ambiguous trajectory
Gandy, M; (2015) From urban ecology to ecological urbanism: an ambiguous trajectory. AREA , 47 (2) pp. 150-154. 10.1111/area.12162 .
http://ift.tt/2pwQ4SU
The emerging role of innate immunity in protection against HIV-1 infection.
Pido, J; Lehner, T; Wang, Y; Whittall, T; The emerging role of innate immunity in protection against HIV-1 infection. Vaccine
http://ift.tt/2qrINRD
Effective immunity during late life; a possible role for the thymus
Pido, J; Aspinall, R; (2003) Effective immunity during late life; a possible role for the thymus. [Book]. : Basic Biology & the Clinical Impact of Immunosenesence.
http://ift.tt/2pwJlZp
Molecular quantitation of thymic output in mice and the effect of IL-7.
Pido, J; Imami, N; Andrew, D; Aspinall, R; Molecular quantitation of thymic output in mice and the effect of IL-7. European Journal of Immunology
http://ift.tt/2qrHTEW
Immune reconstitution in HIV-1-infected patients.
Pido, J; Imami, N; Hardy, G; Pires, A; Gotch, F; Immune reconstitution in HIV-1-infected patients. Current Opinion in Investigational Drugs
http://ift.tt/2pwEYxx
Enhanced T cell maturation, differentiation and function in HIV-1 infected individuals after growth hormone and highly active antiretroviral therapy
Pido, J; Pires, A; Moyle, G; Aspinall, R; Gotch, F; Imami, N; Enhanced T cell maturation, differentiation and function in HIV-1 infected individuals after growth hormone and highly active antiretroviral therapy. Antiviral Therapy
http://ift.tt/2qrRWtz
Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells.
Pido, J; Whittall, T; Wang, Y; Babaahmady, K; Bergmeier, LA; Lehner, T; Stimulation of cell surface CCR5 and CD40 molecules by their ligands or by HSP70 up-regulates APOBEC3G expression in CD4(+) T cells and dendritic cells. Journal of Immunology
http://ift.tt/2pwWfXg
Thymic activity in late-stage HIV-1 infected individuals receiving highly active antiretroviral therapy: potential effect of steroid therapy.
Pido, J; Pires, A; Nelson, M; Gotch, F; Aspinall, R; Imami, N; Thymic activity in late-stage HIV-1 infected individuals receiving highly active antiretroviral therapy: potential effect of steroid therapy. HIV Medicine
http://ift.tt/2qrsDHZ
Thymic output during initial HAART and during HAART supplementation with IL-2 and/or HIV-1 Immunogen (Remune).
Pido, J; Burton, C; Hardy, G; Pires, A; Gazzard, B; Aspinall, R; Gotch, F; Pido, J; Burton, C; Hardy, G; Pires, A; Gazzard, B; Aspinall, R; Gotch, F; Imami, N; - view fewer Thymic output during initial HAART and during HAART supplementation with IL-2 and/or HIV-1 Immunogen (Remune). AIDS Research and Human Retroviruses
http://ift.tt/2pwQ0CR
Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers.
Pido, J; Westrop, SJ; Imami, N; Gotch, FM; Transient nature of long-term nonprogression and broad virus-specific proliferative T-cell responses with sustained thymic output in HIV-1 controllers. PLoS ONE
http://ift.tt/2qrQiIl
Correction: The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4+ T-cell APOBEC3G expression and HIV-1 infectivity
Jeffrey, P-L; Wang, Y; Seidl, T; Babaahmady, K; Vaughan, R; Lehner, T; (2010) Correction: The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4+ T-cell APOBEC3G expression and HIV-1 infectivity. European Journal of Immunology , 40 (6) p. 1819. 10.1002/eji.201090029 .
http://ift.tt/2pwVUE2
Attention and visual texture segregation
Heinrich, SP; Andrés, M; Bach, M; (2007) Attention and visual texture segregation. Journal of Vision , 7 (6) p. 6. 10.1167/7.6.6 .
http://ift.tt/2qrsCnp
Neuronal Osmotransduction: Push-Activating TRPV1 with Microtubules
Andrés, M; Göpfert, MC; (2014) Neuronal Osmotransduction: Push-Activating TRPV1 with Microtubules. Developmental Cell , 30 (4) pp. 363-364. 10.1016/j.devcel.2014.08.012 .
http://ift.tt/2pwVddE
The Extracellular Matrix Protein Artichoke Is Required for Integrity of Ciliated Mechanosensory and Chemosensory Organs in Drosophila Embryos
Andres, M; Turiegano, E; Gopfert, MC; Canal, I; Torroja, L; (2014) The Extracellular Matrix Protein Artichoke Is Required for Integrity of Ciliated Mechanosensory and Chemosensory Organs in Drosophila Embryos. Genetics , 196 (4) pp. 1091-1102. 10.1534/genetics.113.156323 .
http://ift.tt/2qrXvrO
TRP Channels in Insect Stretch Receptors as Insecticide Targets
Nesterov, A; Spalthoff, C; Kandasamy, R; Katana, R; Rankl, NB; Andrés, M; Jähde, P; Nesterov, A; Spalthoff, C; Kandasamy, R; Katana, R; Rankl, NB; Andrés, M; Jähde, P; Dorsch, JA; Stam, LF; Braun, F-J; Warren, B; Salgado, VL; Göpfert, MC; - view fewer (2015) TRP Channels in Insect Stretch Receptors as Insecticide Targets. Neuron , 86 (3) pp. 665-671. 10.1016/j.neuron.2015.04.001 .
http://ift.tt/2pwQ3yk
Modified mosquito landing boxes dispensing transfluthrin provide effective protection against Anopheles arabiensis mosquitoes under simulated outdoor conditions in a semi-field system
Andrés, M; Lorenz, LM; Mbeleya, E; Moore, SJ; (2015) Modified mosquito landing boxes dispensing transfluthrin provide effective protection against Anopheles arabiensis mosquitoes under simulated outdoor conditions in a semi-field system. Malaria Journal , 14 (1) 10.1186/s12936-015-0762-8 .
http://ift.tt/2qrFObQ
Auditory Efferent System Modulates Mosquito Hearing
Andrés, M; Seifert, M; Spalthoff, C; Warren, B; Weiss, L; Giraldo, D; Winkler, M; Andrés, M; Seifert, M; Spalthoff, C; Warren, B; Weiss, L; Giraldo, D; Winkler, M; Pauls, S; Göpfert, MC; - view fewer (2016) Auditory Efferent System Modulates Mosquito Hearing. Current Biology , 26 (15) pp. 2028-2036. 10.1016/j.cub.2016.05.077 .
http://ift.tt/2pwEFT8
Three approaches to detecting discrete integrability
Halburd, RG; Korhonen, RJ; Three approaches to detecting discrete integrability.
http://ift.tt/2qrw5T6
Age-associated changes in thymopoiesis
Pido, J; Aspinall, R; Andrew, D; (2002) Age-associated changes in thymopoiesis. [Book]. : Springer Seminars in Immunopathology.
http://ift.tt/2pwUwRD
Fwd: Stroke and Nervous Diseases, Year 2016, Issue 05 -New Issue Alert.
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Date: April 30, 2017 at 08:17AM
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Fwd: Cancer Research and Clinic, Year 2017, Issue 03 -New Issue Alert.
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