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- Should patients with NAFLD/NASH be surveyed for HCC?
- The use of smartphone for liver graft biopsy asses...
- Penoscrotal swelling—an unusual occurrence in a pa...
- ‘No visible lesions?’—an unusual case of Intestina...
- A case of extensive hepatic adenomatosis in a rena...
- Pneumoperitoneum caused by tubo-ovarian abscess in...
- Primary dural lymphoma mimicking meningioma: a cli...
- Adjuvant radiation for T1-2N1 oral cavity cancer s...
- Correction to: High PD-L1 expression indicates poo...
- Flavored tobacco to E-cigarette’s: How the tobacco...
- Short Stay Thyroid Surgery: Can We Replicate the S...
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Ετικέτες
Κυριακή 5 Αυγούστου 2018
Should patients with NAFLD/NASH be surveyed for HCC?
https://ift.tt/2AKDeYH
Penoscrotal swelling—an unusual occurrence in a patient with an anastomotic leak following ileostomy closure
https://ift.tt/2neENV3
‘No visible lesions?’—an unusual case of Intestinal metaplasia of the bladder
https://ift.tt/2vHDYb0
A case of extensive hepatic adenomatosis in a renal transplant patient
https://ift.tt/2LVFfXf
Pneumoperitoneum caused by tubo-ovarian abscess in an elderly patient
https://ift.tt/2vECvT6
Primary dural lymphoma mimicking meningioma: a clinical and surgical case report
https://ift.tt/2LTHKJm
Adjuvant radiation for T1-2N1 oral cavity cancer survival outcomes and utilization treatment trends: Analysis of the SEER database
Publication date: October 2018
Source: Oral Oncology, Volume 85
Author(s): Vanessa Torrecillas, Hailey M. Shepherd, Sam Francis, Luke O. Buchmann, Marcus M. Monroe, Shane Lloyd, Donald Cannon, Ying J. Hitchcock, John R. Weis, Jason P. Hunt, Jeffrey J. Houlton, Richard B. Cannon
Abstract
Objective
Evaluate current practice patterns in the use of adjuvant radiation for T1-2N1 OCSCC patients and investigate its efficacy in the population-based setting.
Materials and methods
This study extracted patients who were treated surgically for T1N1 and T2N1 OCSCC without adverse nodal features from the SEER database from 2004 to 2013. Patients with distant metastatic disease, unknown surgery or radiation status, or prior malignancies were excluded. Patients were divided into those who underwent surgical resection with and without adjuvant radiation. Disease-specific survival (DSS) and overall survival (OS) were the primary outcomes measured.
Results
746 patients met inclusion criteria and 70% received adjuvant radiation therapy. Treatment with adjuvant radiation therapy was significantly associated with improved 5-year DSS (65% versus 51%; p < 0.001) and OS (54% versus 44%; p = 0.007) for T1N1 tumors. Likewise, improved 5-year DSS (58% versus 38%; p = 0.009) and OS (48% versus 28%; p = 0.004) was shown in T2N1 tumors. Patients with T2N1 tumors wer significantly more likely to receive adjuvant radiation (75% versus 63%; p < 0.001). Those with insurance and high risk primary subsites: buccal, retromolar trigone, and hard palate were more likely to receive adjuvant radiation. The percent utilization of adjuvant radiation remained constant through the study period for T2N1 tumors (72–74%) but significantly decreased for T1N1 (71–55%) (p = 0.047).
Conclusion
Adjuvant radiation therapy is independently associated with a significant survival benefit for patients with both T1N1 and T2N1 OCSCC. However, this study demonstrates that patients with T1N1 cancer are less likely to receive adjuvant radiation and utilization is decreasing.
https://ift.tt/2ndop7b
Correction to: High PD-L1 expression indicates poor prognosis of HIV-infected patients with non-small cell lung cancer
The graphs are incorrectly identified in Fig. 3i, s and should be replaced with the following.
https://ift.tt/2LUTThi
Flavored tobacco to E-cigarette’s: How the tobacco industry sustains its product flow
Publication date: Available online 5 August 2018
Source: Oral Oncology
Author(s): A. Thirumal Raj, Shankargouda Patil, Archana A. Gupta, G. Suveetha
https://ift.tt/2vknuXg
Short Stay Thyroid Surgery: Can We Replicate the Same in Low Resource Setting?
Introduction. The concept of short stay thyroidectomy has been tested and in practice in the developed world; the same has not been replicated in countries with limited resources due to lack of organized healthcare system. So, in this study, we tried to analyze if short stay thyroid surgery can be performed in a cost-effective way in developing countries and also if the endocrine surgical trainee can deliver these services safely. Methods. The study was conducted prospectively from January 2013 to July 2014, at Department of Endocrine Surgery, SGPGIMS, Lucknow, India. Study group included patients undergoing short stay hemithyroidectomy whereas matched patients who qualified for inclusion criteria but did not undergo short stay surgery due to various reasons constituted control group. Outcome in both the groups was compared in terms of complication rates, cost benefit, and patient satisfaction. Subgroup analysis was also done for trainee versus consultant performed short stay thyroid surgery. Results. A total of 439 patients with surgical thyroid disorders were evaluated at our institute during the study period and out of these 110 patients (58 cases and 52 controls) fulfilled the inclusion criteria. Younger patients with low socioeconomic status who were paying out of pocket were found to be more inclined to short stay thyroid surgery. There was no significant difference between the two groups in terms of postanesthetic discharge score (PADS), complication rates, and patients satisfaction; however there was significant reduction (p
https://ift.tt/2vE4Ngm