Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Τετάρτη 17 Φεβρουαρίου 2016
Nutrition and lifestyle in European adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study
Adolescence is a critical period, because major physical and psychologic changes occur during a very short period of time. Changes in dietary habits may induce different types of nutritional disorders and are likely to track into adulthood. The aim of this review is to describe the key findings related to nutritional status in European adolescents participating in the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study. We performed a cross-sectional study in 3528 (1845 females) adolescents aged 12.5-17.5 y. Birth weight was negatively associated with abdominal fat mass in adolescents and serum leptin concentrations (in female adolescents), providing additional evidence for a programming effect of birth weight on energy homeostasis control. Breakfast consumption was associated with lower body fat content and healthier cardiovascular profile. Adolescents eat half of the recommended amount of fruit and vegetables and less than two-thirds of the recommended amount of milk and milk products but consume more meat and meat products, fats, and sweets than recommended. For beverage consumption, sugar-sweetened beverages, sweetened milk, low-fat milk, and fruit juice provided the highest amount of energy. Although the intakes of saturated fatty acids (FAs) and salt were high, the intake of polyunsaturated FAs was low. Adolescents spent, on average, 9 h/d of their waking time (66-71% and 70-73% of the registered time in boys and girls, respectively) in sedentary activities. Factors associated with adolescents' sedentary behavior included the following: 1) age; 2) media availability in the bedroom; 3) sleeping time; 4) breakfast consumption; and 5) season. Sedentary time was also associated with cardiovascular risk factors and bone mineral content. In European adolescents, deficient concentrations were identified for plasma folate (15%), vitamin D (15%), pyridoxal 5'-phosphate (5%), beta-carotene (25%), and vitamin E (5%). Scientists and public health authorities should raise awareness of the importance of a healthy and sustainable lifestyle as a foundation of the health of the European population, now and in the future.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/20DQcYU
via IFTTT
Abatacept experience in steroid and rituximab-resistant focal segmental glomerulosclerosis
Primary focal segmental glomerular sclerosis (FSGS), one of the major causes of nephrotic syndrome, eventually results in end-stage renal disease. Currently, FSGS is treated with immunosuppressive therapies, which include calcinuerin inhibitors (cyclosporine), glucocorticoids, B-cell depleting agents (rituximab) and, recently, a T-cell co-stimulatory inhibitor (abatacept). Until recently, there had been no cases reporting resistance to all current therapies. We report a case of a 62-year-old Caucasian man with biopsy-proven FSGS, who responded well to oral prednisolone therapy. However, 2 years later, he had a relapse and failed to respond to prednisolone. Subsequent treatments then included cyclosporine, rituximab and cyclophosphamide, which were not successful. The patient was then administered abatacept, a novel T-cell co-stimulatory inhibitor—though he did not experience any side effects, there was no change in proteinuria nor in creatinine.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/20DQcIB
via IFTTT
Extramedullary plasmacytoma of the gingiva
Description
Extraosseous plasmacytoma, also referred to as extramedullary plasmacytoma (EMP), is defined by ICD-10 as a localised plasma cell neoplasm that arises in tissues other than bone.1 It is considered one of the three variants of plasma cell neoplasms, the other two being multiple myeloma (MM) and solitary bone plasmacytoma (SBP) (also known as medullary plasmacytoma).
EMP is a relatively rare lesion, constituting 3% of all plasma cell neoplasms.2 About 1% of head and neck tumours are EMPs. It is found most commonly in the head and neck region, with 80% of cases occurring in the nasopharynx, paranasal sinuses and tonsils.3 EMPs occur less commonly in the gingiva. The first case was documented by Martinelli and Rulli4 in 1968 as a sessile neoplasm in the gingiva from the lower left to right canine, which could be confused with chronic gingivitis....
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1opOC1a
via IFTTT
Management of a severe case of Gitelman syndrome with poor response to standard treatment
Gitelman syndrome is an autosomal recessive distal renal tubular disorder caused by defective sodium chloride transporters. Biochemically, it presents with hypokalaemic metabolic alkalosis, hypomagnesaemia and hypocalciuria. It is usually managed with oral potassium supplements and potassium-sparing diuretics. We report a case of a 28-year-old woman whose condition worsened during pregnancy; she became resistant to standard management after delivery of her second child. She was managed in a specialist metabolic clinic through a comprehensive approach including perseverance with oral potassium supplement, weekly intravenous potassium and magnesium infusion, correction of vitamin D level and the offering of appropriate dietary advice; this controlled the patient's symptoms and prevented repeated hospital admissions. In this case report, we illustrate a patient's presentation and diagnosis with Gitelman syndrome, discuss triggers of exacerbation, review the relevant literature in terms of differential diagnoses and provide practical advice on the management of difficult cases in a specialist clinic.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/20DQb7e
via IFTTT
Enquiring About Tolerance (EAT) study: Feasibility of an early allergenic food introduction regimen
Publication date: Available online 17 February 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Michael R. Perkin, Kirsty Logan, Tom Marrs, Suzana Radulovic, Joanna Craven, Carsten Flohr, Gideon Lack
BackgroundThe influence of early exposure to allergenic foods on the subsequent development of food allergy remains uncertain.ObjectiveWe sought to determine the feasibility of the early introduction of multiple allergenic foods to exclusively breast-fed infants from 3 months of age and the effect on breastfeeding performance.MethodsWe performed a randomized controlled trial. The early introduction group (EIG) continued breastfeeding with sequential introduction of 6 allergenic foods: cow's milk, peanut, hard-boiled hen's egg, sesame, whitefish (cod), and wheat; the standard introduction group followed the UK infant feeding recommendations of exclusive breastfeeding for around 6 months with no introduction of allergenic foods before 6 months of age.ResultsOne thousand three hundred three infants were enrolled. By 5 months of age, the median frequency of consumption of all 6 foods was 2 to 3 times per week for every food in the EIG and no consumption for every food in the standard introduction group (P < .001 for every comparison). By 6 months of age, nonintroduction of the allergenic foods in the EIG was less than 5% for each of the 6 foods. Achievement of the stringent per-protocol consumption target for the EIG proved more difficult (42% of evaluable EIG participants). Breastfeeding rates in both groups significantly exceeded UK government data for equivalent mothers (P < .001 at 6 and at 9 months of age).ConclusionEarly introduction, before 6 months of age, of at least some amount of multiple allergenic foods appears achievable and did not affect breastfeeding. This has important implications for the evaluation of food allergy prevention strategies.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHe1BU
via IFTTT
Comment on "Virtues and limitations of Pittsburgh green for ozone detection" by C. C. Beltran, E. A. Palmer, B. R. Buckley and F. Iza, Chem. Commun., 2015, 51, 1579
Chem. Commun., 2016, Advance Article
DOI: 10.1039/C5CC08289G, Comment
DOI: 10.1039/C5CC08289G, Comment
Upamanyu Basu, Kazunori Koide
Ozonolysis of Pittsburgh Green homoallyl ether was studied in detail under various reaction conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
Ozonolysis of Pittsburgh Green homoallyl ether was studied in detail under various reaction conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Xxx3Ib
via IFTTT
the iconography of Lumumba in the arts and the work of Raoul Peck
A two-days bilingual international conference (February 18-19, 2016), organized by the University of Antwerp,1 with keynote speaker Raoul Peck and Johannes Fabian. Organisation: Matthias De Groof and Kathleen Gyssels, Antwerp University.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1KWgV11
via IFTTT
Point triangulation through polyhedron collapse using the l∞ norm
Multi-camera triangulation of feature points based on a minimisation of the overall l2 reprojection error can get stuck in suboptimal local minima or require slow global optimisation. For this reason, researchers have proposed optimising the l∞ norm of the l2 single view reprojection errors, which avoids the problem of local minima entirely. In this paper we present a novel method for l∞ triangulation that minimizes the l∞ norm of the l∞ reprojection errors: this apparently small difference leads to a much faster but equally accurate solution which is related to the MLE under the assumption of uniform noise. The proposed method adopts a new optimisation strategy based on solving simple quadratic equations. This stands in contrast with the fastest existing methods, which solve a sequence of more complex auxiliary Linear Programming or Second Order Cone Problems. The proposed algorithm performs well: for triangulation, it achieves the same accuracy as existing techniques while executing faster and being straightforward to implement.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Xxx2Ef
via IFTTT
Fast and robust variational optical flow for high-resolution images using SLIC superpixels
We illustrate how a pixel-based method can be directly applied on a near-regular grid of segments (superpixels) from a well-chosen image segmentation. This allows the accelerated processing of high-resolution content with existing pixel-based methods, which might not be able to process it in its input resolution in the first place. In essence, the superpixel segmentation is a tool to decrease the dimensionality of the input image without significant loss of quality for the final result. We show how optical flow estimation, whose execution time is often of vital importance, can benefit from this workflow for processing 4K content whilst also conferring a degree of noise robustness: this pre-processing is a novel direction of research for the field. Naturally, the application of this concept is not restricted to optical flow: it is applicable in many different fields.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1KWgTX2
via IFTTT
Adjuvante hormonale behandeling van het hormoongevoelige mammacarcinoom: update
Er zijn verschillende mogelijkheden als het gaat over de adjuvante hormonale behandeling van het hormoongevoelige borstcarcinoom bij de pre- en de postmenopauzale patiënte. Hoewel tamoxifen de standaardtherapie is, bestaat er nog een andere optie voor de postmenopauzale vrouw, namelijk de aromataseremmers (AI) van de derde generatie: anastrozol, letrozol en exemestan. In dit artikel worden een overzicht gegeven en een vergelijking gemaakt van de verschillende huidige adjuvante hormonale behandelingen die beschikbaar zijn voor de pre- en de postmenopauzale vrouw met borstkanker.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Xxx2E4
via IFTTT
Acute ataxie: een zeldzame diagnose?
The medical history of a three-year-old boy with acute ataxia due to the opsoclonus-myoclonusataxia syndrome (short: opsoclonus-myoclonus syndrome (OMS)) is presented. The further diagnostic investigation reveals an associated thoracic neuroblastoma. In children with acute ataxia, the diagnosis of OMS is rare, difficult and often unrecognized in the beginning. In half of the children with OMS, an associated neuroblastoma is present. Further investigation for an associated neuroblastoma is always indicated when the diagnosis of OMS is set.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1KWgTWX
via IFTTT
Accurate modeling of the predicted kESM-based link performance metric for BIC-OFDM systems
Effective SNR mapping (ESM) is a powerful technique for optimizing the performance of orthogonal frequency division multiplexing (OFDM) based wireless systems. ESM transforms a vector of subcarrier SNRs into a scalar effective SNR, which represents the SNR that would yield the same error performance in an equivalent system operating over an additive white Gaussian noise (AWGN) channel. This technique significantly simplifies the development of adaptive coding and modulation (ACM) algorithms. As the distribution of the effective SNR, when only imperfect and outdated channel state information (CSI) is available, cannot be expressed in closed form, we develop an approximate statistical model which is based on the beta distribution. Our model is compared in terms of approximation accuracy against models based on the Gaussian distribution, the gamma distribution and the more complex Pearson and generalized extreme value (GEV) distributions.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Xxx2nK
via IFTTT
BPMN extensions for decentralized execution and monitoring of business processes
Software-as-a-service (SaaS) providers are further expanding their offering by growing into the space of business process outsourcing (BPO). Therefore, the SaaS provider wants to administer and manage the business process steps according to a service level agreement. Outsourcing of business processes results in decentralized business workflows. However, current business process modeling languages, e.g. Business Process Execution Language (BPEL), Business Process Model and Notation (BPMN), are based highly on a centralized execution model and current BPMN engines offer limited constructs for federation and decentralized execution. To guarantee execution of business processes according to a service level agreement, different parties involved in a federated workflow must be able to inspect the state of external workflows. This requires advanced inspection interfaces and monitoring facilities. Current business process modeling languages must thus be extended to support monitoring in the s pecification, support modeling and support deployment of decentralized workflows. In this paper, correlation and monitoring extensions for BPMN are described. These extensions to BPMN are described such that the existing specification can still be used as is in a backwards compatible way.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1KWgTWN
via IFTTT
Optimalisatie van de verkeersongevallenstatistieken. Inleiding tot STRADA.
De huidige Belgische registratie is ondermaats zodat geen representatieve en betrouwbare gegevens meer beschikbaar zijn. Hierdoor is de opbouw van een verkeersveiligheidsbeleid in België moeilijk omdat verschillende verkeersdeelnemers of leeftijds-groepen totaal ondervertegenwoordigd zijn in de statistieken. Dit probleem dat door velen werd onderkend, kon echter op onvol-doende begrip rekenen in sommige middens. Nog steeds kan vastgesteld worden dat de waarschuwing over de betrouw-baarheid van het statistisch materiaal, wordt beschouwd als een negatieve boodschap die men best onder de mat schuift. Veelal wordt de boodschapper geviseerd in plaats van dat men het probleem van onderrapportering aanpakt. Zo werd zeer onlangs op een Belgisch congres een bijdrage over dit thema geweigerd omdat het een negatieve boodschap was en omdat de huidige ongevalcijfers reeds slecht genoeg zijn. Dit voortdurend ontkennen van de onvolledigheid en gebrek aan representativiteit van de verkeersongevallencijfers staat in schril kontrast met eisen die gewoonlijk aan statistisch materiaal worden gesteld. Polak 1 geeft aan dat de bruikbaarheid en de waarde van registraties afhangen van negen aspecten: volledigheid of representativiteit, correctheid, relevantie, resolutie, nauwkeurig-heid, tijdigheid, continuïteit, flexibiliteit en koppelbaarheid. Het probleem van de waarde van de registratie is een probleem dat zich in de meeste landen stelt maar in een aantal landen heeft men via aanvullende technieken (bv. grootschalige enquêtes die voor ophoging en voor representativiteitssituering kunnen zorgen) de foutmarge en de representativiteit van verschillende verkeersdeelnemers kunnen verfijnen. In België stelt men vast dat direct betrokkenen het probleem kenden maar geen enkele onderzoek lieten uitvoeren om de "statistische onveiligheid" beter in beeld te brengen. Met het onderzoek "Optimalisatie van de verkeersongevallensta-tistieken" wordt gepoogd om de ongevalstatistieken terug een betrouwbaarheidskarakter te geven. Daarenboven kan bij een volledige implementatie en aanwending van alle technieken, het registratiewerk van politie sterk verminderd worden. Daarenboven kan het op termijn de basis zijn voor het berekenen van de maatschappelijke kost van verkeersongevallen voor de gemeen-schap. Belangrijk is dat in ontwerpen van de Staten-Generaal voor de Verkeersveiligheid dit onderzoek als essentieel wordt beschouwd voor betere en betrouwbare statistieken.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Xxx3b2
via IFTTT
Omega-3 fatty acids as an adjunct for periodontal therapy—a review
Abstract
Objectives
The aim of this article is to present an overview of omega-3 fatty acids, their anti-inflammatory properties and potential use as an adjunct for periodontal therapy.
Materials and methods
A general literature search was conducted to provide an overview of omega-3 fatty acids, their metabolism and anti-inflammatory properties. A more specific literature search of PubMed and EMBASE was conducted to identify articles dealing studies investigating the effects of omega-3 fatty acids in the treatment of periodontitis in animals and humans and included cross-sectional, longitudinal and intervention designs.
Results
To date, there is good emerging evidence that dietary supplementation with fish oil may be of some benefit and this is enhanced if combined with aspirin. All clinical intervention studies to date have been on small sample sizes, and this indicates there is need for larger and more robust clinical trials to verify these initial findings.
Conclusions
Dietary supplementation with fish oil could be a cost-effective adjunctive therapy to the management of periodontal disease.
Clinical relevance
The host modulatory properties of omega-3 fatty acids warrant further assessment of their use as an adjunct in the management of periodontitis.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1LtpH1z
via IFTTT
Clarity in Denoting Mass Spectrometric Peptide Ions
A recent paper published by Chu et al. (2015) gives an overview of work presented at the Mass Spectrometry and Proteomics Workshop held at the University of Hong Kong in December 2014.1 The paper contains proposals for improving the nomenclature used to describe peptide ions resulting from mass spectrometry analysis. The authors intend that the new Read the rest of this article
The post Clarity in Denoting Mass Spectrometric Peptide Ions appeared first on Accelerating Science.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Tqp1By
via IFTTT
The role of MR enterography in the evaluation of non-Crohn’s pathologies
Source:Seminars in Ultrasound, CT and MRI
Author(s): Nyree Griffin, Olwen Westerland
In the young patient population, MR enterography is fast becoming a preferred imaging tool for the investigation of patients with non-Crohn's small bowel and mesenteric pathologies. Its advantages include lack of ionising radiation and high contrast resolution. This review will discuss the range of small bowel and mesenteric pathologies that can be easily demonstrated with this technique.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1U7DFND
via IFTTT
Non-destructive testing techniques to evaluate the healing efficiency of self-healing concrete at lab-scale
Within the European FP7 project HEALCON, Non-Destructive Testing (NDT) and monitoring techniques are developed and combined to characterize the effects of self-healing mechanismsin small and full-size specimens. In the first stage, healing mechanisms were evaluated at lab-scale. Specimens containing encapsulated polymer precursors were cracked and reloaded after the healing period. During loading, healing and reloading, NDT techniques (acoustic emission analysis, vibration analysis and ultrasonic measurement) were applied to help understanding the cracking behavior, capsule breakage and healing efficiency. Moreover, the effect of the flexibility of the polymeric healing agent on the crack re-opening during reloading was investigated on cracked and healed mortar specimens, using acoustic emission and digital image correlation techniques. The results show the applicability of NDT methods to evaluate the self-healing efficiency for small specimens. Comparing the NDT techniques, some of them (e.g. ultrasound) seem to be good candidates for in situ monitoring of the healing efficiency.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1QkNsQQ
via IFTTT
From a biological sample to high-quality digital image representation: avoiding and restoring image artifacts through proper acquisition and image restoration
The objective of modern microscopy is to acquire high-quality image based data sets. A typical microscopy workflow is set up in order to address a specific biological question and involves different steps: sample preparation, image acquisition, image storage, restoration (if necessary) and analysis. In order to analyze the images and draw scientific conclusions, it is crucial to obtain image data that reflects reality as close as possible. We provide an overview of the fundamental artifacts and degradations that affect many micrographs during the acquisition and storage phase: non-uniform illumination, blur, noise, digitization and compression. Image restoration techniques such as flat-field correction, deconvolution and denoising can manipulate the acquired data in an effort to reduce the impact of artifacts due to physical and technical limitations, resulting in a better representation (i.e. a more accurate correspondence to reality) of the object of interest. However, precise usage of these algorithms is necessary in order to not introduce further artifacts that might influence the data-analysis and bias the conclusions. For example, high compression rates may result into small file sizes, but typically introduce blocking artifacts that might affect consecutive image segmentation. It is essential to understand image acquisition and storage, and how it introduces artifacts and degradations in the acquired data, so that their effects on subsequent analysis can be minimized. We describe why artifacts appear, in what sense they impact overall image quality and how to mitigate them by first improving the acquisition parameters and then applying proper image restoration techniques.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaQKq
via IFTTT
Gewichtsverlies bij kinderen: waaraan denken en hoe aanpakken
Weight loss in children: which diagnosis to think about and how to handle The interpretation of „insufficient weight" and the differential diagnosis of weight loss in children have many differences when compared to the approach for adults. In children, weight stagnation, poor weight gain and weight loss have to be taken seriously since it is often the first symptom of an underlying disease. To interpret a child's weight in a correct manner, it is crucial to use weight and height percentiles. A minimum of technical examinations besides an anamnesis and a clinical examination is necessary. A dietary intake will be needed to evaluate a sufficient intake. A stool examination for parasites, a urine examination, a blood test with antibodies for coeliac disease and a measurement of the faecal calprotectin above the age of five are the first-line technical investigations. This manuscript is a centre-based expertise on how to handle weight loss in children, using case-reports as an example.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaT8V
via IFTTT
Robust sensorless load angle control for stepping motors
In industry, the bulk of the stepping motors is driven in open loop full-step mode with maximum current to avoid step loss. This results in noisy operation due to torque ripples and a poor energy-efficiency. To tackle these problems the current current level at which the stepping motor is driven can be reduced to an optimal level. In this paper, a sensorless load angle controller is proposed and implemented to optimise the drive current level. However, reducing the current level results in a diminished torque margin for load disturbances. In this paper, a countermeasure to enhance the robustness of the sensorless load angle controller against torque disturbances is proposed and assessed trough measurements.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1QkNqZa
via IFTTT
Energy efficiency measurement procedure for gearboxes in their entire operating range
Over the last decade, forced regulations and a growing social awareness with respect to energy efficiency have resulted in a renewed interest in the research for high efficient electrical machines. When an electrical motor is coupled to a machine, in many cases a gearbox or belt transmission is used. Research shows a lack of information on energy efficiency of these components. In comparison to electrical motors and drives, there is very few regulation and if efficiency values can be found in catalogues, there is no regulated test procedure available to validate the data. As a result, the reliability of these efficiency values is unknown and comparison between manufacturers and technologies is impossible. In this paper a test bench is proposed to measure the energy efficiency of a gearbox with an accuracy up to 0.4%. The test bench is used to measure the efficiency of gearboxes in their entire speed and torque range. Contour maps are used to visualize these measurement results. Moreover, a measurement campaign using different gearboxes is carried out to compare the energy efficiency in the manufacturers catalogue and the measured efficiency.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaQtT
via IFTTT
Geen woorden, maar daden: de politie moet het goede voorbeeld geven
Ouders die verkeersregels aan hun laars lappen, geven hun kin-deren het slechte voorbeeld. Ook beleidsdragers en beleidsuit-voerders zijn zich niet genoeg bewust van hun voorbeeldfunctie. Door signalen te geven die aanzetten tot onveilig gedrag, dreigen ze sensibiliseringscampagnes zinloos te maken.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaQtL
via IFTTT
Verkeershandhaving en -vervolging moeten gekaderd worden binnen het verkeersveiligheidsbeleid
Een verkeersveihgheidsbeleid kan de complexiteit van de ver-keersonveiligheid niet doeltreffend aanpakken als het zich slechts op één beleidsmiddel richt. Het heeft pas kans op slagen als men de verschillende beleidsmiddelen op een verstandige manier combineert en vooral op elkaar afstemt. Handhaving is geen doel op zich, maar enkel een middel. In die mate dat het eerder als ondersteunend dan als sturend moet worden beschouwd. Binnen het verkeersveihgheidsbeleid moet in eerste instantie worden gepleit voor maatregelen die onveiligheidgedrag kunnen voorkomen. Bij die maatregelen staan infrastructuur en voertuig centraal, maar een belangrijke rol moet ook worden toegedicht aan de bestuurder (opleiding, rij-inzicht, ...). Handhaving en vervolging spelen net een zeer belangrijke rol in de blijvende verankering van het gedrag van de bestuurder in verkeersveilig-heidsopties. Handhavingsbeleid moet echter ook gericht zijn op het opbouwen van kennis over de effecten van infrastructuur en voertuig op de verkeersveiligheid. Data uit ongevallenstatistieken, maar evenzeer uit de analyse van verkeersinbreuken, zijn voor de wegbeheerders en de voertuigconstructeurs basiselementen (of zouden dit moeten zijn) om hun rol in het veiligheidsbeleid bij te sturen.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1QkNs3c
via IFTTT
Steeds sneller, steeds zwaarder: onderzoek naar vermogen, topsnelheid, gewicht en kracht van auto's
Het toenemend aantal auto's zorgt niet alleen voor veel doden en gewonden op de weg, maar het speelt ook een belangrijke rol in de milieuvervuiling. Door het feit dat auto's ook steeds meer ver-mogen, kracht, gewicht en een hogere topsnelheid ontwikkelen, zullen beide problemen niet snel opgelost worden. In dit artikel wordt de evolutie van deze vier elementen (ver-mogen, kracht, gewicht en een hogere topsnelheid) van 1983 tot en met 1999 onderzocht. De resultaten van bet onderzoek staan in sterk contrast met de huidige beleidsmaatregelen om snelheid (en daarmee samen-hangend het aantal doden en gewonden) en emissies drastisch te verlagen.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaNyf
via IFTTT
Aanvaardbaarheid van de maximale snelheidsbegrenzer
Dit rapport is het resultaat van een onderzoek dat uitgevoerd werd in het kader van een DWTC-project. Dit project "NAAR EEN DRAAGVLAK VOOR EEN VOERTUIG-TECHNISCHE SNELHEIDS-BEHEERSING BINNEN EEN INTRINSIEK VEILIGE VERKEERS-OMGEVING" had als doel om te onderzoeken welke nieuwe snelheidsbeheersingsmaatregelen kunnen uitgewerkt worden. Vooral maatregelen die de snelheid aan banden leggen via in-car-technieken en via categorisering van wegen, maakten het voor-werp uit van dit onderzoek. De bestaande snelheidsmaatregelen -in casu de maximale snel-heidsbegrenzer in autocars en vrachtwagens vormen een belang-rijk referentiepunt. Immers uit de aanvaardbaarheid van de snelheidsbegrenzer kunnen lessen getrokken worden die bruik-baar zijn wanneer een intelligente snelheidsbegrenzer voor alle voertuigen wordt ingevoerd. Dit rapport brengt verslag uit over het onderzoek naar de satis-factie bij beroepschauffeurs en vervoerbedrijven over de maxi-male snelheidsbegrenzer in autocars (> 10 ton) en vrachtwagens (> 12 ton). Dit rapport wil lessen trekken uit de amateuristische manier waar-op de maximale snelheidsbegrenzer in België is ingevoerd en te-zelfdertijd aangeven hoe uit de gemaakte fouten, beleidsaanbe-velingen voor een versterken van het draagvlak voor ISA kunnen gehaald worden. Het onderzoek bij de beroepschauffeurs werd uitgevoerd met medewerking van de vakorganisaties in de vervoersector. Een aselecte keuze van vervoerbedrijven maakte het mogelijk een geografisch gespreid beeld te hebben van de meningen van de bedrijven. De selectie van de bedrijven probeerde een zo goed mogelijk representatief beeld te geven op basis van de grootte van het vervoerbedrijf (aantal werknemers). De onderzoeksresultaten geven een niet zo flatterend beeld van het correct gebruik van de maximale snelheidsbegrenzer door de vervoersector. De publicatie van enkele besluiten heeft tot hevige reacties geleid van de autocarsector zonder dat enig controleer-baar gegeven werd ingebracht. Op basis van de resultaten van deze studie worden in deel III beleidsaanbevelingen gepubliceerd. De bedoeling is dat enerzijds bij het invoeren van een nieuwe maatregel zoals ISA de nodige begeleidings- en draagvlakversterkende maatregelen worden genomen en anderzijds dat de bestaande reglementering wordt aangepast zodat via handhaving, controlemechanismen en aan-gepaste bestraffing een correcte naleving wordt bekomen. Daarenboven wordt in deze nota ook aangegeven hoe op korte en lange termijn bepaalde nieuwe evoluties kunnen verwacht worden en hoe het beleid zich daarop moet voorbereiden.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaPWR
via IFTTT
Is het statistische materiaal even onveilig als het verkeer ? Onderzoek objectieve onveiligheid (deel 1)
Zo goed als altijd staan er cijfers aan de basis van een beleid. Oat is niet anders wat betreft verkeer en de (on)veiligheid ervan. In België blijken die cijfers niet volledig en niet representatief te zijn: er kan dus geen kwaliteitsgarantie gegeven worden. Onder andere het BIVV en de mobiliteitscel zullen zich moeten afvragen in welke mate er nog sprake is van kwaliteitsvol beleidsadvies als men zich baseert op zulke statistische gegevens. Waar loopt het mis? Hoe kunnen de problemen aangepakt worden op korte en lange termijn?
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1QkNqbx
via IFTTT
Beleidsaanbevelingen
Uit de studie 'Impact van de verkeersonveiligheid en. -onleefbaar-heid' kunnen een aantal beleidsaanbevelingen worden afgeleid. Die aanbevelingen hebben betrekking op enerzijds het statistisch materiaal en anderzijds het beleid van de verkeersveiligheid.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaPGn
via IFTTT
Nitride tuning of lanthanide chromites
Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC00744A, Communication
DOI: 10.1039/C6CC00744A, Communication
Ashley Phillip Black, Hannah Johnston, Judith Oro-Sole, Bernat Bozzo, Clemens Ritter, Carlos Frontera, Paul Attfield, Amparo Fuertes
LnCrO3-xNx perovskites with Ln = La, Pr and Nd and nitrogen contents up to x = 0.59 have been synthesised through ammonolysis of LnCrO4 precursors. These new materials represent one...
The content of this RSS Feed (c) The Royal Society of Chemistry
LnCrO3-xNx perovskites with Ln = La, Pr and Nd and nitrogen contents up to x = 0.59 have been synthesised through ammonolysis of LnCrO4 precursors. These new materials represent one...
The content of this RSS Feed (c) The Royal Society of Chemistry
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaPGc
via IFTTT
The synthesis and efficient one-pot catalytic "self-breeding" of asymmetrical NC(sp3)E-hybridised pincer complexes
Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC00763E, Communication
DOI: 10.1039/C6CC00763E, Communication
Xiangyuan Yang, Wee Shan Tay, Yongxin Li, Sumod A Pullarkat, Pak-Hing Leung
Cyclopalladation of the pyridyl-substituted chiral phosphine sulfide (N-P=S) and oxide (N-P=O) ligands afforded the asymmetric N-C(sp3)*-S and N-C(sp3)*-O pincer complexes. When applied as catalysts in asymmetric hydrophosphination, the newly developed...
The content of this RSS Feed (c) The Royal Society of Chemistry
Cyclopalladation of the pyridyl-substituted chiral phosphine sulfide (N-P=S) and oxide (N-P=O) ligands afforded the asymmetric N-C(sp3)*-S and N-C(sp3)*-O pincer complexes. When applied as catalysts in asymmetric hydrophosphination, the newly developed...
The content of this RSS Feed (c) The Royal Society of Chemistry
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaNhC
via IFTTT
Metal ion triggers for reversible switching of DNA polymerase
Chem. Commun., 2016, Accepted Manuscript
DOI: 10.1039/C6CC00454G, Communication
DOI: 10.1039/C6CC00454G, Communication
Ki Soo Park, Chang Yeol Lee, Hyun Gyu Park
We herein develop a new strategy that modulates DNA polymerase activity in a reversible and switchable manner by using the novel interactions between DNA bases and metal ions (T-Hg2+-T and...
The content of this RSS Feed (c) The Royal Society of Chemistry
We herein develop a new strategy that modulates DNA polymerase activity in a reversible and switchable manner by using the novel interactions between DNA bases and metal ions (T-Hg2+-T and...
The content of this RSS Feed (c) The Royal Society of Chemistry
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1mHaPpM
via IFTTT
Pattern identification of biomedical images with time series: Contrasting THz pulse imaging with DCE-MRIs
Publication date: Available online 16 February 2016
Source:Artificial Intelligence in Medicine
Author(s): Xiao-Xia Yin, Sillas Hadjiloucas, Yanchun Zhang, Min-Ying Su, Yuan Miao, Derek Abbott
ObjectiveWe provide a survey of recent advances in biomedical image analysis and classification from emergent imaging modalities such as terahertz (THz) pulse imaging (TPI) and dynamic contrast-enhanced magnetic resonance images (DCE-MRIs) and identification of their underlining commonalities.MethodsBoth time and frequency domain signal pre-processing techniques are considered: noise removal, spectral analysis, principal component analysis (PCA) and wavelet transforms. Feature extraction and classification methods based on feature vectors using the above processing techniques are also discussed. These include Mahalanobis distance, support vector machine (SVM) and extreme learning machine (ELM) classifiers.ValidationExamples where the proposed methodologies have been successful in classifying TPIs and DCE-MRIs are discussed.ResultsIdentifying commonalities in the structure of such heterogeneous datasets potentially leads to a unified multi-channel signal processing framework for biomedical image analysis.ConclusionThe proposed complex valued classification methodology enables fusion of entire datasets from a sequence of spatial images taken at different time stamps; this is of interest from the viewpoint of inferring disease proliferation. The approach is also of interest for other emergent multi-channel biomedical imaging modalities and of relevance across the biomedical signal processing community.
from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1LtnXoZ
via IFTTT
Εγγραφή σε:
Αναρτήσεις (Atom)