Concurrent Chemoradiotherapy With or Without Adjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma Patients at High Risk of Distant Metastasis

Condition:   Local Advanced High Risk Nasopharyngeal Carcinoma
Interventions:   Drug: IMRT combine with cisplatin concurrent chemotherapy;   Drug: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Sponsor:   Zhao Chong
Not yet recruiting - verified November 2016

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Early Detection of Esophageal Cancer

Conditions:   Esophageal Neoplasms;   Stomach Neoplasms;   Endoscopy, Gastrointestinal;   Digestive System Endoscopic Surgical Procedures;   Cytology
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified December 2015

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A flux-difference finite volume method for steady Euler equations on adaptive unstructured grids

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Upstream and downstream processing in biotechnology III

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Correlation between clinical and MRI assessment of depth of invasion in oral tongue squamous cell carcinoma

Neck metastasis is the most important prognostic factor in oral cavity squamous cell carcinomas (SCC). Apart from the T- stage, depth of invasion has been used as a highly predictable factor for microscopic ne...

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True abscess formation is rare in bacterial orbital cellulitis; consequences for treatment

Publication date: Available online 24 November 2016
Source:American Journal of Otolaryngology
Author(s): Eline G. Van der Veer, Nicolien A. van der Poel, Maartje M.L. de Win, Roel J. Kloos, Peerooz Saeed, Maarten P. Mourits
BackgroundPre- or retroseptal bacterial orbital cellulitis (pOC/rOC) is not an uncommon orbital disease. Treatment consists of antibiotics with or without surgical drainage. Several questions regarding course, complications and outcome of treatment are unanswered and the indication for surgery is not well defined. The aim of this study is to: 1. describe the outcome of orbital cellulitis (OC) in a large cohort, 2. assess the significance of Chandler's classification, 3. assess the incidence of abscess formation in OC, and 4. redefine criteria for surgery.MethodsRetrospective case series of patients with OC seen between 1-1-2007 and 1-1-2014 in a tertiary referral center.ResultsSixty-eight patients presented with (presumed) bacterial pOC. Two out of these 68 developed rOC. All 68 patients had a full recovery. Forty-eight patients presented with rOC. Four out of 48 (8%) had intracranial extension of the infection at the time of admission. No admitted patient developed distant seeding. Only four (8%) patients with rOC had a true orbital abscess. In the other 92% we found a diffuse orbital inflammation or a subperiosteal empyema. Forty-four (92%) patients with rOC had a full recovery.Conclusions1. The prognosis of both pOC and rOC nowadays is generally favorable. 2. Chandler's classification is of little use. 3. True abscess formation in OC is rare. 4. The indication for surgical intervention must be based on the clinical presentation and the assessment of true orbital abscess formation.



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Corrigendum to “Methylene blue staining in the parotid surgery: Randomized trial, 144 patients” [Am J Otolaryngol 37 (2016) 22–26]

Publication date: Available online 23 November 2016
Source:American Journal of Otolaryngology
Author(s): Michael Vaiman, Basel Jabarin, Rani Abuita




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