Primary mucosal melanoma of the palatine tonsil: Report of a case and review of the literature

Publication date: Available online 21 April 2017
Source:American Journal of Otolaryngology
Author(s): Marcela Osorio, Sami P. Moubayed, Juan Hernandez-Prera, John Scott, Mark L. Urken
BackgroundMucosal melanoma of the palatine tonsil is extremely rare. Due to its poor prognosis, primary tonsillar melanoma requires prompt recognition and treatment.MethodsA 62-year old female presented with a deeply pigmented and exophytic lesion in the left tonsillar fossa. The patient underwent a partial pharyngectomy through a midline labio-mandibulotomy approach along with a left level I–V neck dissection. Reconstruction with a left radial forearm free flap and a pharyngeal constrictor advancement pharyngoplasty was performed.ResultsThe patient remains free of disease at eight months after adjuvant proton therapy and eleven months after surgery. To our knowledge, less than thirty cases have been either reported or referenced in the literature since the early 1900′s. This report is the first in English literature to compile all reported cases of primary tonsillar melanoma.ConclusionCurrently, evidence suggests that mucosal melanoma in the palatine tonsil should be treated in the same fashion as other head and neck mucosal melanomas, mindful of the high rates at which locoregional and distant metastases occur.



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