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Τετάρτη 3 Μαΐου 2017

IgA pemphigus - lumping or splitting?

Abstract

Unlike the progress that has been achieved in understanding the complex molecular basis of pemphigus vulgaris (PV)1, the pathogenesis of IgA pemphigus (IGAP) remains elusive. Hashimoto et al.2 described 49 IGAP cases and their immuno-phenotype based on extensive laboratory workup. In their study, only one patient was found to have multiple myeloma and none had concomitant solid malignancies, which may bear implications regarding optimal workup in IGAP.

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