Simultaneous Resection of Multiple Metastatic Brain Tumors with Multiple Keyhole Craniotomies.

Related Articles

Simultaneous Resection of Multiple Metastatic Brain Tumors with Multiple Keyhole Craniotomies.

World Neurosurg. 2017 Jun 23;:

Authors: Baker CM, Glenn CA, Briggs RG, Burks JD, Smitherman AD, Conner AK, Williams AE, Malik MU, Algan O, Sughrue ME

Abstract
BACKGROUND: The proper management of symptomatic patients with two or more brain metastases is not entirely clear and the surgical outcomes of these patients undergoing multiple simultaneous craniotomies have not been well described. In this manuscript, we describe patient outcomes after simultaneously resecting metastatic lesions through multiple keyhole craniotomies.
METHODS: We conducted a retrospective review of data obtained on all patients undergoing resection of multiple brain metastases in one operation between 2014 and 2016. We describe a technique for resecting multiple metastatic lesions and share the patient outcomes of this operation.
RESULTS: Twenty patients with 46 tumor resections were included in the study. The primary site of metastases for the majority of patients was lung, followed by melanoma, renal, breast, colon and testicular. Nine of 20 (45%) patients had two preoperative intracranial lesions and 11 (55%) had three or more. Karnofsky performance scales were calculated for 14 patients: postoperatively 10/14 (71%) scores improved, 2/14 (14%) worsened and 2/14 (14%) remained unchanged. After surgery 9/14 (64%) patients were weaned off steroids by 2 month follow-up. The overall median survival time from date of surgery was 10.8 months.
CONCLUSIONS: We present patient outcomes after simultaneously resecting metastatic brain tumors through multiple keyhole craniotomies in symptomatic patients. Our results suggest comparable outcomes and similar surgical risk to those undergoing resection of single BM. Resection of multiple BM may improve KPS in the early post-operative period and allow patients to be weaned from steroids.

PMID: 28652117 [PubMed - as supplied by publisher]

from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/2tjUyyo
via IFTTT