Characterization of the complete nucleotide sequences of IMP-4-encoding plasmids, belonging to diverse Inc families, recovered from Enterobacteriaceae of wildlife origin [PublishAheadOfPrint]

The complete nucleotide sequences of six IMP-4-encoding plasmids recovered from Enterobacteriaceae of wildlife origin were characterized. Sequencing data showed that plasmids of different incompatibility groups (IncM, IncI1, IncF, and nontypeable [including an IncX5_2 and two pPrY2001-like]) carried the bla_IMP-4-carrying integrons, In809 or In1460. Most of the plasmids carried mph(A) region, and chrA-like, aac(3)-IId and bla_TEM-1b genes. Finally, plasmid analysis revealed the involvement of two different, IS26- and Tn1696-associated, mechanisms in the mobilization of IMP-4-encoding integrons.

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