Clinical Efficacy of Percutaneous Transhepatic Portal Vein Angioplasty for Late-Onset Portal Vein Stenosis in Pediatric Liver Transplant Patients

AbstractBackgroundStenosis of the portal vein (PV) is a rare complication after liver transplantation (LT) in pediatric patients and it adversely affects outcomes. We reviewed the safety and efficacy of percutaneous transhepatic balloon angioplasty (PTBA) as a treatment for post-LT late-onset portal vein stenosis (PVS).Methods318 patients between the ages of 0-21 years received a LT from 2001 to 2016 at this tertiary center. 21 children were evaluated for PVS using percutaneous portal venography.ResultsOf the 21, 19 patients (7F:12M) with median age 12years (7-15) were diagnosed with PVS and received PTBA. Two patients were excluded: one did not have PVS; one received shunt surgery. Median time between LT and PTBA was 83months (IQR:49-138). For patients in whom pressure could be accurately measured (n=9), mean PV pressure gradient was 6.3mmHg (SD:5.0) pre-procedure and 0.9mmHg (SD:1.2) postprocedure. Mean percentage improvement in gradient across the stenotic region was 86.2% (SD:15.9%; p

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