The present observation sheds new light on the pathogenesis of bradykinin-mediated angioedema by showing that local involvement occurs hours after systemic kallikrein-kinin activation. Therefore, biological diagnostic workup is of greatest value when performed at the very early phase of the attack.
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Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
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Πέμπτη 3 Μαΐου 2018
Angioedema: systemic activation process during prodromes
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